منابع مشابه
Make or break for mitochondria
Ensuring that mitochondrial DNA is successfully divided between daughter mitochondria involves a complex series of interactions with the endoplasmic reticulum and a variety of enzymes.
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1. SAPPHIRE Group, Health Sciences, University of Leicester, UK 2. Paediatric Emergency Medicine Leicester Academic Group (PEMLA) Emergency Department, Leicester Royal Infirmary, Leicester, UK 3. Emergency Department, Central Manchester University Hospitals NHS Foundation Trust, Cobbett House, Manchester Royal Infirmary, Oxford Rd, Manchester, UK 4. Bristol Royal Hospital for Children, Emergenc...
متن کاملMake It or Break It: Manipulating Robustness in Large Networks
The function and performance of networks rely on their robustness, defined as their ability to continue functioning in the face of damage (targeted attacks or random failures) to parts of the network. Prior research has proposed a variety of measures to quantify robustness and various manipulation strategies to alter it. In this paper, our contributions are twofold. First, we critically analyze...
متن کاملBreak to Make a Connection
Meiosis is the cell division program utilized by most sexually reproducing organisms as a strategy to produce haploid gametes (i.e., sperm and eggs) from diploid parental cells. As suggested by its name, which stems from the Greek word meaning ‘‘to diminish or reduce’’, meiosis reduces the chromosome number by half. This is accomplished by following a single round of DNA replication with two co...
متن کاملMake-or-break: chasing risky goals or settling for safe rewards?
Humans regularly invest time towards activities characterized by dramatic success or failure outcomes, where critically, the outcome is uncertain ex-ante. How should people allocate time between such make-or-break activities and other safe alternatives, where rewards are more predictable (e.g., linear) functions of time? We present a formal framework for studying time allocation between these t...
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ژورنال
عنوان ژورنال: Science
سال: 2010
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.327.5968.923-c